SCHEMBL11567192

SCHEMBL11567192

N#CC(Cl)Cc1cccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2D6 P10635 2/20 0.42
PIP4K2A P48426 1/20 0.40
ACP3 P15309 1/20 0.40
ALDH1A1 P00352 3/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
SLC6A4 P31645 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
OPRL1 P41146 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31450593 0.82 CTNNB1 (0.49) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL197908 0.82 CTNNB1 (0.49) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL15096098 0.82 CTNNB1 (0.49) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL15096099 0.82 CTNNB1 (0.49) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL14720291 0.81 CTNNB1 (0.47) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL16933753 0.79 CYP1A2 (0.52) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL27627250 0.79 CYP1A2 (0.46) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL6445137 0.79 CTNNB1 (0.45) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL28978071 0.76 PIP4K2A (0.47) CTNNB1TDP1CYP1A2CYP2C19CYP2C9
SCHEMBL6445960 0.76 CTNNB1 (0.46) CTNNB1TDP1CYP1A2CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4145362-A DIAZOTIZATION OF ARYLAMINE IN PRESENCE OF ALKANOIC ACID, COPPER HALIDE CATALYST S.A. P R B EN NEERLANDAIS PRB N.V. (BE) 1979-03-20 US disclosed