Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031356 | 0.87 | HAO1 (0.61) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 | |
| SCHEMBL2354500 | 0.86 | HAO1 (0.64) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 | |
| SCHEMBL11218955 | 0.85 | HAO1 (0.71) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 | |
| SCHEMBL28606431 | 0.83 | ALDH1A1 (0.67) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 | |
| SCHEMBL9352992 | 0.82 | HAO1 (0.77) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 | |
| SCHEMBL1790000 | 0.80 | ALDH1A1 (0.59) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 | |
| SCHEMBL9788805 | 0.80 | HAO1 (0.64) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 | |
| SCHEMBL9356350 | 0.80 | HAO1 (0.73) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 | |
| SCHEMBL2944396 | 0.80 | ALDH1A1 (0.59) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 | |
| SCHEMBL27832625 | 0.80 | HAO1 (0.64) | HAO1ALDH1A1SMN1; SMN2MAPTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000644-A2 | Lower cycloalkyl substituted-benzene derivatives, the preparation thereof and their pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-02-07 | — | — | EP | disclosed |