Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.55 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.53 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566486 | 0.95 | SIGMAR1 (0.55) | SIGMAR1NPFFR1NPFFR2OPRM1OPRD1 | |
| SCHEMBL9148987 | 0.92 | NPFFR1 (0.61) | SIGMAR1NPFFR1NPFFR2OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL11565432 | 0.90 | NPFFR1 (0.60) | SIGMAR1NPFFR1NPFFR2OPRM1OPRD1 | |
| SCHEMBL11566761 | 0.89 | NPFFR1 (0.54) | SIGMAR1NPFFR1NPFFR2OPRM1OPRD1 | |
| SCHEMBL11563945 | 0.88 | NPFFR1 (0.53) | SIGMAR1NPFFR1NPFFR2OPRM1OPRD1 | |
| SCHEMBL11568096 | 0.88 | SIGMAR1 (0.55) | SIGMAR1NPFFR1NPFFR2OPRM1SMN1; SMN2 | |
| SCHEMBL11564641 | 0.84 | NPFFR1 (0.53) | SIGMAR1NPFFR1NPFFR2SMN1; SMN2 | |
| SCHEMBL11566955 | 0.84 | NPFFR1 (0.53) | SIGMAR1NPFFR1NPFFR2OPRM1OPRD1 | |
| SCHEMBL11567994 | 0.82 | HRH3 (0.52) | SIGMAR1NPFFR1NPFFR2OPRM1OPRD1 | |
| SCHEMBL3167579 | 0.79 | NPFFR1 (0.60) | SIGMAR1NPFFR1NPFFR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |