Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | FAP | Q12884 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 6/20 | 0.38 |
| ▸ | REN | P00797 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313551 | 0.92 | PREP (0.54) | PREPFAPF2XIAPACE | |
| SCHEMBL8053385 | 0.85 | ACE (0.54) | PREPFAPF2ACEREN | |
| SCHEMBL11760610 | 0.85 | ACE (0.54) | PREPFAPF2ACEREN | |
| SCHEMBL7886313 | 0.81 | ELANE (0.47) | PREPFAPF2XIAPACE | |
| SCHEMBL13019614 | 0.80 | PREP (0.48) | PREPFAPACEACE2CPA1 | |
| SCHEMBL8053091 | 0.80 | PREP (0.43) | PREPFAPF2XIAPACE | |
| SCHEMBL8053098 | 0.80 | PREP (0.43) | PREPFAPF2XIAPACE | |
| SCHEMBL11440574 | 0.79 | PREP (0.61) | PREPFAPF2XIAPACE | |
| SCHEMBL31181299 | 0.79 | CPA1 (0.47) | PREPFAPF2XIAPACE | |
| SCHEMBL8052318 | 0.79 | PREP (0.42) | PREPFAPF2XIAPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153688-A | N-TRIFLUOROACETYL-ALANYL OR LYSYL-ALANYL OR LYSYL-ANILIDE, REVERSIBLE ELASTASE ENZYME INHIBITORS | DELALANDE S.A. (FR) | 1979-05-08 | — | — | US | disclosed |