Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564169 | 0.93 | PPARA (0.46) | PPARGPPARASLC22A12ABCB11CYP1A2 | |
| SCHEMBL11640145 | 0.89 | PPARG (0.43) | PPARGPPARANPSR1SLC22A12HPGD | |
| SCHEMBL11565230 | 0.87 | PPARG (0.45) | PPARGPPARANPSR1SLC22A12FNTA | |
| SCHEMBL11566782 | 0.85 | PPARA (0.45) | PPARGPPARASLC22A12ABCB11CYP1A2 | |
| SCHEMBL11566518 | 0.84 | KMT2A (0.45) | PPARGPPARASLC22A12ABCB11CYP1A2 | |
| SCHEMBL11562245 | 0.82 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL11642266 | 0.82 | PPARA (0.43) | PPARGPPARANPSR1SLC22A12ABCB11 | |
| SCHEMBL11565539 | 0.80 | F10 (0.47) | PPARGSLC22A12LMNAHTT | |
| SCHEMBL11643884 | 0.80 | PPARA (0.41) | PPARGPPARASLC22A12ABCB11CYP1A2 | |
| SCHEMBL11565815 | 0.79 | GAA (0.39) | PPARGPPARANPSR1SLC22A12ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | claimed |