Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 5/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564169 | 0.85 | PPARA (0.46) | EPHX2ABCB11LMNAPPARGSLC22A12 | |
| SCHEMBL11567643 | 0.79 | PPARG (0.46) | NPSR1EPHX2ABCB11LMNAMAPT | |
| SCHEMBL11565539 | 0.79 | F10 (0.47) | LMNAPPARGSLC22A12 | |
| SCHEMBL11566782 | 0.78 | PPARA (0.45) | EPHX2MEN1KMT2AABCB11PPARG | |
| SCHEMBL11566518 | 0.76 | KMT2A (0.45) | SMN1; SMN2MEN1KMT2ASLC6A4ABCB11 | |
| SCHEMBL11642266 | 0.74 | PPARA (0.43) | SMN1; SMN2NPSR1EPHX2ABCB11LMNA | |
| SCHEMBL11643884 | 0.72 | PPARA (0.41) | EPHX2ABCB11LMNAMAPTPPARG | |
| SCHEMBL11565422 | 0.72 | F9 (0.46) | MEN1KMT2AMAPTPPARGSLC22A12 | |
| SCHEMBL11566210 | 0.72 | PPARG (0.54) | ABCB11LMNAPPARGSLC22A12PPARA | |
| SCHEMBL11642190 | 0.71 | BCL2L1 (0.44) | SMN1; SMN2LMNAMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168385-A | LOWERING OF STEROL AND TRIGLYCERIDE SERUM LEVELS | AMERICAN CYANAMID COMPANY (US) | 1979-09-18 | — | — | US | claimed |