Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 15/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 3/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564878 | 0.90 | HCAR3 (0.83) | HCAR3NPC1RAB9AGRM5HCAR2 | |
| SCHEMBL71308 | 0.85 | HCAR3 (1.00) | HCAR3NPC1RAB9AGRM5HCAR2 | |
| SCHEMBL11561979 | 0.84 | HCAR3 (0.73) | HCAR3NPC1RAB9AGRM5 | |
| SCHEMBL11563504 | 0.84 | HCAR3 (0.73) | HCAR3GRM5 | |
| SCHEMBL11564806 | 0.84 | HCAR3 (0.73) | HCAR3NPC1RAB9AGRM5HCAR2 | |
| SCHEMBL11565571 | 0.84 | HCAR3 (0.73) | HCAR3NPC1GRM5HCAR2 | |
| SCHEMBL14341697 | 0.82 | HCAR3 (0.76) | HCAR3HCAR2 | |
| SCHEMBL26436204 | 0.82 | HCAR3 (0.76) | HCAR3GRM5HCAR2AURKA | |
| SCHEMBL1520623 | 0.81 | HCAR3 (0.64) | HCAR3NPC1RAB9AGRM5HCAR2 | |
| SCHEMBL11584100 | 0.80 | HCAR3 (0.68) | HCAR3NPC1RAB9AGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000816-A1 | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-02-21 | — | — | EP | disclosed |