Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.77 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.75 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.58 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564229 | 0.91 | OPRM1 (0.65) | OPRM1OPRD1OPRK1 | |
| Oxalic Acid SCHEMBL6045561 | 0.88 | OPRM1 (0.83) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| Oxalic Acid SCHEMBL11563217 | 0.87 | OPRM1 (0.81) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| SCHEMBL11566707 | 0.87 | OPRM1 (0.85) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| Hydrochloric Acid SCHEMBL11565270 | 0.87 | OPRM1 (0.81) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| Carfentanil SCHEMBL116222 | 0.86 | OPRM1 (1.00) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| [11C]-Carfentanil SCHEMBL29374424 | 0.86 | OPRM1 (1.00) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| SCHEMBL11564677 | 0.85 | OPRM1 (0.79) | OPRM1OPRD1OPRK1CACNA1COPRL1 | |
| SCHEMBL11563515 | 0.85 | OPRM1 (0.78) | OPRM1OPRD1OPRK1CACNA1C | |
| Carfentanil SCHEMBL4256090 | 0.85 | OPRM1 (0.98) | OPRM1OPRD1OPRK1CACNA1COPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |