Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568715 | 0.91 | TSHR (0.45) | MAPTALDH1A1HPGDTSHRNPSR1 | |
| SCHEMBL15525136 | 0.88 | ALDH1A1 (0.55) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11568711 | 0.83 | MAPT (0.41) | MAPTGRM6ALDH1A1MEN1KMT2A | |
| SCHEMBL11567522 | 0.75 | CNR2 (0.40) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5150367 | 0.74 | CYP1A2 (0.45) | ALDH1A1MEN1KMT2AHPGDTSHR | |
| SCHEMBL11572113 | 0.73 | ALDH1A1 (0.49) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL11570115 | 0.73 | HSP90AA1 (0.47) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL12323480 | 0.73 | TSHR (0.40) | MAPTALDH1A1HPGDTSHRGAA | |
| SCHEMBL11568036 | 0.72 | MAPT (0.47) | MAPTALDH1A1KMT2AHPGDNPSR1 | |
| SCHEMBL11004733 | 0.72 | ALDH1A1 (0.58) | MAPTGRM6ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002881-A1 | 5-Isoxazolylurea derivatives, their preparation, their use and compositions containing them | FISONS plc (GB) | 1979-07-11 | — | — | EP | claimed |
| EP-0002881-A1 | 5-Isoxazolylurea derivatives, their preparation, their use and compositions containing them | FISONS plc (GB) | 1979-07-11 | — | — | EP | disclosed |