Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 10/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911962 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2PDE3BPDE3ANPC1RAB9A | |
| SCHEMBL7273949 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2PDE3BPDE3APDE2AKCNH2 | |
| SCHEMBL8791532 | 0.84 | AXL (0.58) | SMN1; SMN2NPC1RAB9ALMNACYP1A2 | |
| SCHEMBL2986346 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2PDE3BPDE3APDE2AKCNH2 | |
| SCHEMBL17103799 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2PDE3BPDE3APDE2AKCNH2 | |
| SCHEMBL2798028 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2PDE3BPDE3APDE2AKCNH2 | |
| SCHEMBL3412583 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2PDE3BPDE3APDE2AKCNH2 | |
| SCHEMBL17832848 | 0.73 | KDM4E (0.59) | SMN1; SMN2NPC1RAB9ALMNACYP1A2 | |
| SCHEMBL11254453 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2PDE3BPDE3APDE2AKCNH2 | |
| SCHEMBL10353452 | 0.71 | SMN1; SMN2 (0.81) | SMN1; SMN2PDE3BPDE3APDE2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136184-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS | SANDOZ, INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4055644-A | CNS DEPRESSANTS | SANDOZ, INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3931176-A | CNS DEPRESSANT | SANDOZ INC. (US) | 1976-01-06 | — | — | US | disclosed |