Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568392 | 1.00 | AGTR1 (0.49) | AGTR1ESR2KMT2AMEN1HPGD | |
| SCHEMBL3068936 | 0.89 | AGTR1 (0.55) | AGTR1ESR2KMT2AMEN1HPGD | |
| SCHEMBL6280202 | 0.89 | AGTR1 (0.55) | AGTR1ESR2KMT2AMEN1HPGD | |
| SCHEMBL10910459 | 0.81 | ESR2 (0.68) | ESR2KMT2AMEN1ALOX12RAB9A | |
| SCHEMBL4401106 | 0.79 | ESR2 (0.71) | ESR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL4402311 | 0.79 | ESR2 (0.71) | ESR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL19844907 | 0.78 | ESR2 (0.53) | AGTR1ESR2KMT2AMEN1HPGD | |
| SCHEMBL12336909 | 0.78 | ESR2 (0.69) | ESR2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL4862366 | 0.78 | NPC1 (0.57) | KMT2ARAB9ANPC1PKMCDK5 | |
| SCHEMBL20198257 | 0.76 | ESR2 (0.66) | ESR2KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148983-A | TERTIARY CATALYST SYSTEM INCLUDING AN ORGANOMETALLIC COMPOUND, A CHROMIUM COMPOUND AND AN ORGANIC PHOSPHITE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-04-10 | — | — | US | disclosed |