⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13555402 | 1.00 | — | — | |
| Methane SCHEMBL397821 | 0.91 | CA1 (0.33) | — | |
| SCHEMBL2304709 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL4116846 | 0.91 | — | — | |
| Methane SCHEMBL818106 | 0.84 | CA1 (0.30) | — | |
| Formaldehyde SCHEMBL15406088 | 0.79 | — | — | |
| Nitrous Acid SCHEMBL7205839 | 0.79 | — | — | |
| SCHEMBL3392178 | 0.74 | — | — | |
| SCHEMBL15811753 | 0.71 | — | — | |
| SCHEMBL13250831 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301340-A1 | MICELLE RELEASING THERMOSENSITIVE HYDROGELS AS A THERAPEUTIC DELIVERY SYSTEM | Georgia Tech Research Corporation (US) | 2024-01-10 | — | — | EP | claimed |
| CN-115501204-B | Preparation method of hyaluronic acid nano drug delivery system for cascade drug delivery | 河北工业大学 | 2023-07-21 | — | — | CN | claimed |
| CN-115501204-A | Preparation method of hyaluronic acid nano drug delivery system for cascade drug delivery | 河北工业大学 | 2022-12-23 | — | — | CN | claimed |
| EP-1439187-B1 | O2-ARYLATED OR O2-GLYCOSYLATED 1-SUBSTITUTED DIAZEN-1-IUM-1,2-DIOLATES AND O2-SUBSTITUTED 1- (2-CARBOXYLATO)PYRROLIDIN-1-YL DIAZEN-1-IUM-1,2-DIOLATES | US HEALTH (US) | 2013-12-18 | — | — | EP | claimed |
| EP-2632255-A1 | DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES | Merck Sharp & Dohme Corp. (US) | 2013-09-04 | — | — | EP | claimed |
| WO-2012058203-A1 | DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | claimed |
| US-20080288176-A1 | Development of Prodrugs Possessing a Nitric Oxide Donor Diazen-1-Ium-1,2-Diolate Noiety Using in Vitro/in Silico Predictions | TAM YUN KAU | 2008-11-20 | — | — | US | claimed |
| WO-2025230641-A1 | NITRIC OXIDE-RELEASING LIPOSOMES AS THERAPY FOR RESPIRATORY INFECTIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2025-11-06 | — | — | WO | disclosed |
| EP-3936608-B1 | REPROGRAMMING CELLS | SCRIPPS RESEARCH INST (US) | 2025-05-07 | — | — | EP | disclosed |
| US-20240139104-A1 | MICELLE RELEASING THERMOSENSITIVE HYDROGELS AS A THERAPEUTIC DELIVERY SYSTEM | GEORGIA TECH RESEARCH CORPORATION | 2024-05-02 | — | — | US | disclosed |
| US-11807529-B1 | Photosensitized release of nitric oxide | UNIVERSITY OF PUERTO RICO (US) | 2023-11-07 | — | — | US | disclosed |
| CN-115501204-B | Preparation method of hyaluronic acid nano drug delivery system for cascade drug delivery | 河北工业大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-110198959-B | Nitric oxide releasing alginate as biodegradable antimicrobial scaffolds and related methods | 北卡罗米纳大学查佩尔希尔分校 | 2023-03-28 | — | — | CN | disclosed |
| WO-2003056899-A9 | NITRIC OXIDE DONORS FOR TREATMENT OF DISEASE AND INJURY | FORD HENRY HEALTH SYSTEM (US) | 2004-04-15 | — | — | WO | disclosed |
| WO-2003095398-A2 | POLYDIAZENIUMDIOLATED CYCLIC POLYAMINES WITH POLYPHASIC NITRIC OXIDE RELEASE AND RELATED COMPOUNDS, COMPOSITIONS COMPRISING SAME AND METHODS OF USING SAME | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003056899-A2 | NITRIC OXIDE DONORS FOR TREATMENT OF DISEASE AND INJURY | HENRY FORD HEALTH SYSTEM (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20020004498-A1 | Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction | DOHERTY PAUL C (US) | 2002-01-10 | — | — | US | disclosed |
| US-20010046471-A1 | Infrared thermograpy and methods of use | NICOX S.A. (FR) | 2001-11-29 | — | — | US | disclosed |
| US-6147068-A | RELEASING NITRIC OXIDE | THE UNIVERSITY OF AKRON (US) | 2000-11-14 | — | — | US | disclosed |
| WO-1999065563-A1 | ELECTRICALLY ASSISTED TRANSDERMAL METHOD AND APPARATUS FOR THE TREATMENT OF ERECTILE DYSFUNCTION | GENETRONICS, INC. (US) | 1999-12-23 | — | — | WO | disclosed |