⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156928 | 0.74 | — | — | |
| SCHEMBL13555402 | 0.74 | — | — | |
| Formaldoxime SCHEMBL19086140 | 0.74 | — | — | |
| SCHEMBL2304709 | 0.68 | — | — | |
| Methane SCHEMBL397821 | 0.68 | CA1 (0.33) | — | |
| SCHEMBL4532239 | 0.68 | — | — | |
| SCHEMBL15821667 | 0.68 | — | — | |
| Ammonia Solution, Strong SCHEMBL4116846 | 0.68 | — | — | |
| SCHEMBL9219479 | 0.67 | — | — | |
| SCHEMBL9705842 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8894985-B2 | Nitric oxide-releasing polymers | AMULET PHARMACEUTICALS, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20110059036-A1 | NITRIC OXIDE-RELEASING POLYMERS | AMULET PHARMACEUTICALS, INC. | 2011-03-10 | — | — | US | disclosed |
| US-7829553-B2 | generation of NO from a C-based diazeniumdiolate that is covalently attached to a phenyl-containing polymer( polystyrene homo or copolymer, polyethyene terephthalate, polyamides etc.) without the possibility to form nitrosamines; of vascular stents, vascular grafts, catheters, wound dressings, bandages | AMULET PHARMACEUTICALS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| EP-1968615-A1 | NITRIC OXIDE-RELEASING POLYMERS | Amulet Pharmaceuticals, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| US-20070286840-A1 | generation of NO from a C-based diazeniumdiolate that is covalently attached to a phenyl-containing polymer( polystyrene homo or copolymer, polyethyene terephthalate, polyamides etc.) without the possibility to form nitrosamines; of vascular stents, vascular grafts, catheters, wound dressings, bandages | AMULET PHARMACEUTICALS, INC. | 2007-12-13 | — | — | US | disclosed |
| US-20070196327-A1 | Nitric oxide releasing polymers | AMULET PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
| WO-2007067477-A1 | NITRIC OXIDE-RELEASING POLYMERS | AMULET PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |
| EP-1718316-A2 | NITRIC OXIDE-RELEASING POLYMERS | Amulet Pharmaceuticals, Inc. (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005081752-A2 | NITRIC OXIDE-RELEASING POLYMERS | AMULET PHARMACEUTICALS, INC. (US) | 2005-09-09 | — | — | WO | disclosed |