SCHEMBL11569448

SCHEMBL11569448

N#Cc1ccccc1NC=N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.48
TSHR P16473 3/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
GAA P10253 4/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
GLA P06280 1/20 0.40
CYP1A2 P05177 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PDK1 Q15118 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK3 Q15120 1/20 0.39
PDK4 Q16654 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28746777 0.78 KDM4E (0.48) KDM4ETSHRHPGDHSD17B10GAA
SCHEMBL5779162 0.78 KDM4E (0.49) KDM4ETSHRHPGDHSD17B10GAA
SCHEMBL30804592 0.77 KDM4E (0.55) KDM4ETSHRHPGDHSD17B10GAA
SCHEMBL395135 0.77 KDM4E (0.55) KDM4ETSHRHPGDHSD17B10GAA
SCHEMBL30804597 0.77 KDM4E (0.55) KDM4ETSHRHPGDHSD17B10GAA
SCHEMBL11497098 0.73 KDM4E (0.52) KDM4ETSHRHPGDHSD17B10GAA
SCHEMBL11321889 0.73 KDM4E (0.52) KDM4ETSHRHPGDHSD17B10GAA
SCHEMBL22593389 0.73 KDM4E (0.52) KDM4ETSHRHPGDHSD17B10GAA
SCHEMBL1343863 0.73 KDM4E (0.52) KDM4ETSHRHPGDHSD17B10GAA
SCHEMBL1781557 0.73 KDM4E (0.52) KDM4ETSHRHPGDHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154755-A Manufacture of N-(2-cyanophenyl)-formamidines BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US claimed
US-4154755-A Manufacture of N-(2-cyanophenyl)-formamidines BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed
US-4154755-A Manufacture of N-(2-cyanophenyl)-formamidines BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed
US-4154755-A Manufacture of N-(2-cyanophenyl)-formamidines BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed