Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591911 | 0.98 | SCN1A (0.31) | SCN1ASCN2ASCN3A | |
| SCHEMBL11567957 | 0.82 | SLC1A2 (0.32) | SCN1ASCN2ASCN3A | |
| SCHEMBL28363969 | 0.82 | SCN1A (0.31) | SCN1ASCN2ASCN3A | |
| SCHEMBL11085265 | 0.82 | SLC1A2 (0.32) | SCN1ASCN2ASCN3A | |
| SCHEMBL8648894 | 0.80 | — | — | |
| SCHEMBL6822711 | 0.78 | — | — | |
| SCHEMBL6822712 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28676586 | 0.78 | — | — | |
| SCHEMBL29049006 | 0.77 | APLNR (0.30) | — | |
| SCHEMBL12332047 | 0.76 | CYP19A1 (0.40) | SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001774-A1 | Derivatives of BPTI (basic pancreatic trypsin-inhibitor), process for their preparation and their use as medicines | BAYER AG (DE) | 1979-05-16 | — | — | EP | disclosed |