SCHEMBL11569672

SCHEMBL11569672

C#CCOCCCCCCCCCCOCC#C

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11571608 1.00 TSHR (0.56) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL26205671 1.00 TSHR (0.56) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL26205673 1.00 TSHR (0.56) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL11572476 1.00 TSHR (0.56) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL766061 1.00 TSHR (0.56) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL26205674 1.00 TSHR (0.56) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL11572511 1.00 TSHR (0.56) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL17186655 0.97 TSHR (0.58) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL7254965 0.90 TSHR (0.58) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL766216 0.87 TSHR (0.47) TSHRMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192964-A1 Daisy Chain Polymers Synthesized Employing an Energy Ratchet Mechanism NORTHWESTERN UNIVERSITY 2023-06-22 US disclosed
US-20230192964-A1 Daisy Chain Polymers Synthesized Employing an Energy Ratchet Mechanism NORTHWESTERN UNIVERSITY 2023-06-22 US disclosed
WO-2021237250-A1 DAISY CHAIN POLYMERS SYNTHESIZED EMPLOYING AN ENERGY RATCHET MECHANISM NORTHWESTERN UNIVERSITY (US) 2021-11-25 WO disclosed
US-20140170405-A1 PROCESSES FOR PREPARING CURED FILMS, THE RESULTING FILMS, AND PLASMA-INITIATED POLYMERIZABLE COMPOSITIONS FUJIFILM CORPORATION (JP) 2014-06-19 US disclosed
US-20140170405-A1 PROCESSES FOR PREPARING CURED FILMS, THE RESULTING FILMS, AND PLASMA-INITIATED POLYMERIZABLE COMPOSITIONS FUJIFILM CORPORATION (JP) 2014-06-19 US disclosed
US-4137329-A Insecticidal propargyl ethers HOFFMANN-LA ROCHE INC. (US) 1979-01-30 US disclosed