SCHEMBL766216

SCHEMBL766216

C#CCOCCCCCCCCCCCCCCCCCC

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
HTT P42858 5/20 0.46
THRB P10828 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.46
CES2 O00748 2/20 0.43
ALDH1A1 P00352 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
USP2 O75604 1/20 0.41
CES1 P23141 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 2/20 0.38
RAB9A P51151 2/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8745000 1.00 TSHR (0.47) TSHRHTTTHRBMEN1KMT2A
SCHEMBL19519203 1.00 TSHR (0.47) TSHRHTTTHRBMEN1KMT2A
SCHEMBL8745030 1.00 TSHR (0.47) TSHRHTTTHRBMEN1KMT2A
SCHEMBL6141331 1.00 TSHR (0.47) TSHRHTTTHRBMEN1KMT2A
SCHEMBL15096837 1.00 TSHR (0.47) TSHRHTTTHRBMEN1KMT2A
SCHEMBL8027738 1.00 TSHR (0.47) TSHRHTTTHRBMEN1KMT2A
SCHEMBL7147818 1.00 TSHR (0.47) TSHRHTTTHRBMEN1KMT2A
SCHEMBL766010 1.00 TSHR (0.47) TSHRHTTTHRBMEN1KMT2A
SCHEMBL1143522 0.98
SCHEMBL17738112 0.96 HTT (0.54) TSHRHTTTHRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0316618-B1 Multilayer flat light sensitive registration material BASF AG (DE) 1994-08-17 EP claimed
US-9533049-B2 Method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, and the use thereof UNIVERSITE D'AIX-MARSEILLE (FR) 2017-01-03 US disclosed
US-9533049-B2 Method for preparing nanoparticles based on functional amphiphilic molecules or macromolecules, and the use thereof UNIVERSITE D'AIX-MARSEILLE (FR) 2017-01-03 US disclosed
EP-2435031-B1 Functional amphiphilic molecule or macromolecule formulations with multiple compartments UNIV BORDEAUX (FR) 2015-09-16 EP disclosed
EP-2435031-B1 Functional amphiphilic molecule or macromolecule formulations with multiple compartments UNIV BORDEAUX (FR) 2015-09-16 EP disclosed
US-9050268-B2 Functional amphipilic molecule or macromolecule formulations with multiple compartments UNIVERSITE D'AIX-MARSEILLE (FR) 2015-06-09 US disclosed
US-9050268-B2 Functional amphipilic molecule or macromolecule formulations with multiple compartments UNIVERSITE D'AIX-MARSEILLE (FR) 2015-06-09 US disclosed
US-9050268-B2 Functional amphipilic molecule or macromolecule formulations with multiple compartments UNIVERSITE D'AIX-MARSEILLE (FR) 2015-06-09 US disclosed
US-20140308343-A1 METHOD FOR PREPARING NANOPARTICLES BASED ON FUNCTIONAL AMPHIPHILIC MOLECULES OR MACROMOLECULES, AND THE USE THEREOF UNIVERSITE VICTOR SEGALEN BORDEAUX 2 (FR) 2014-10-16 US disclosed
US-20140308343-A1 METHOD FOR PREPARING NANOPARTICLES BASED ON FUNCTIONAL AMPHIPHILIC MOLECULES OR MACROMOLECULES, AND THE USE THEREOF UNIVERSITE VICTOR SEGALEN BORDEAUX 2 (FR) 2014-10-16 US disclosed
US-20120070505-A1 FUNCTIONAL AMPHIPILIC MOLECULE OR MACROMOLECULE FORMULATIONS WITH MULTIPLE COMPARTMENTS UNIVERSITE DE LA MEDITERRANEE (FR) 2012-03-22 US disclosed
US-20110245477-A1 EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS TRUSTEES OF BOSTON COLLEGE (US) 2011-10-06 US disclosed
US-20110059180-A1 Method for Preparing Nanoparticles Based on Functional Amphiphilic Molecules or Macromolecules, and the Use Thereof Universite de Bordeaux (FR) 2011-03-10 US disclosed
US-20110059180-A1 Method for Preparing Nanoparticles Based on Functional Amphiphilic Molecules or Macromolecules, and the Use Thereof Universite de Bordeaux (FR) 2011-03-10 US disclosed
US-20110059180-A1 Method for Preparing Nanoparticles Based on Functional Amphiphilic Molecules or Macromolecules, and the Use Thereof Universite de Bordeaux (FR) 2011-03-10 US disclosed
WO-2010136676-A1 FUNCTIONAL AMPHIPHILIC MOLECULE OR MACROMOLECULE FORMULATIONS WITH MULTIPLE COMPARTMENTS UNIVERSITE VICTOR SEGALEN BORDEAUX 2 (FR) 2010-12-02 WO disclosed
WO-2010136676-A1 FUNCTIONAL AMPHIPHILIC MOLECULE OR MACROMOLECULE FORMULATIONS WITH MULTIPLE COMPARTMENTS UNIVERSITE VICTOR SEGALEN BORDEAUX 2 (FR) 2010-12-02 WO disclosed
EP-2231132-A2 METHOD FOR PREPARING NANOPARTICLES BASED ON FUNCTIONAL AMPHIPHILIC MOLECULES OR MACROMOLECULES, AND THE USE THEREOF Université Victor Segalen Bordeaux 2 (FR) 2010-09-29 EP disclosed
WO-2009098404-A2 METHOD FOR PREPARING NANOPARTICLES BASED ON FUNCTIONAL AMPHIPHILIC MOLECULES OR MACROMOLECULES, AND THE USE THEREOF UNIVERSITE VICTOR SEGALEN BORDEEUX 2 (FR) 2009-08-13 WO disclosed
WO-2009098404-A2 METHOD FOR PREPARING NANOPARTICLES BASED ON FUNCTIONAL AMPHIPHILIC MOLECULES OR MACROMOLECULES, AND THE USE THEREOF UNIVERSITE VICTOR SEGALEN BORDEEUX 2 (FR) 2009-08-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245477-A1 EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS PAICS, COASY, CYP51A1 TSHR 3171/4885HTT 4378/4885THRB 3992/4885
US-20110059180-A1 Method for Preparing Nanoparticles Based on Functional Amphiphilic Molecules or Macromolecules, and the Use Thereof CETP, PCTP, ABCB4 TSHR 3974/4885HTT 1622/4885THRB 4735/4885
US-20140308343-A1 METHOD FOR PREPARING NANOPARTICLES BASED ON FUNCTIONAL AMPHIPHILIC MOLECULES OR MACROMOLECULES, AND THE USE THEREOF CETP, PCTP, ABCB4 TSHR 4010/4885HTT 1694/4885THRB 4709/4885
US-20120070505-A1 FUNCTIONAL AMPHIPILIC MOLECULE OR MACROMOLECULE FORMULATIONS WITH MULTIPLE COMPARTMENTS ANXA2, SLC47A2, ABCB4 TSHR 3691/4885HTT 2229/4885THRB 4694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.