Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.70 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 11/20 | 0.52 |
| ▸ | NPY1R | P25929 | 8/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.52 |
| ▸ | NPY2R | P49146 | 4/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294449 | 1.00 | GNPAT (0.70) | GNPATKISS1RCTSSCTSKNPY4R | |
| SCHEMBL30533200 | 1.00 | GNPAT (0.70) | GNPATKISS1RCTSSCTSKNPY4R | |
| SCHEMBL5966576 | 0.95 | GNPAT (0.64) | GNPATKISS1RNPY4RNPY1RNPY5R | |
| SCHEMBL5966572 | 0.95 | GNPAT (0.64) | GNPATKISS1RNPY4RNPY1RNPY5R | |
| SCHEMBL29569028 | 0.94 | GNPAT (0.62) | GNPATKISS1RNPY4RNPY1RNPY5R | |
| SCHEMBL12792618 | 0.92 | KISS1R (0.62) | GNPATKISS1RNPY4RNPY1RNPY5R | |
| SCHEMBL13563435 | 0.92 | KISS1R (0.62) | GNPATKISS1RNPY4RNPY1RNPY5R | |
| SCHEMBL23177890 | 0.92 | GNPAT (0.60) | GNPATKISS1RNPY4RNPY1RNPY5R | |
| SCHEMBL29391773 | 0.91 | NPY4R (0.62) | GNPATNPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL10381527 | 0.91 | GNPAT (0.57) | GNPATKISS1RNPY4RNPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004589-A2 | Alpha-N-acetyl-L-phenylalanine-L-arginine-ethyl ester, process for its preparation and its use as a diagnostic agent for kallikrein | BAYER AG (DE) | 1979-10-17 | — | — | EP | disclosed |