Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571420 | 0.89 | CTSK (0.41) | CTSKPRKCAPRKCDCTSLCTSB | |
| SCHEMBL11569835 | 0.89 | CTSK (0.45) | CTSKSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL11571149 | 0.88 | CTSK (0.40) | CTSKCTSLCTSB | |
| SCHEMBL11571250 | 0.88 | CTSK (0.40) | CTSKCTSLCTSB | |
| SCHEMBL9370319 | 0.83 | CTSK (0.58) | CTSKCYP1A2PRKCAPRKCDCTSL | |
| SCHEMBL11571422 | 0.79 | CTSK (0.43) | CTSKCTSLCTSB | |
| SCHEMBL11571147 | 0.78 | CTSK (0.42) | CTSKCTSLCTSB | |
| SCHEMBL11570912 | 0.78 | CTSK (0.42) | CTSKCTSLCTSB | |
| SCHEMBL11573127 | 0.75 | CYP1A2 (0.39) | CYP1A2CYP2D6APEX1PMP22ESR1 | |
| SCHEMBL11569696 | 0.75 | S1PR1 (0.44) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175544-A | X-RAYS OF BODY FOR MEDICAL DIAGNOSIS | Lafayette Pharmacal Inc. (US) | 1979-11-27 | — | — | US | disclosed |