Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 1.00 |
| ▸ | CA2 | P00918 | 5/20 | 1.00 |
| ▸ | CES2 | O00748 | 2/20 | 0.70 |
| ▸ | CES1 | P23141 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.65 |
| ▸ | RXRA | P19793 | 1/20 | 0.64 |
| ▸ | PARP1 | P09874 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.64 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.64 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.64 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Anisic Acid SCHEMBL43335 | 1.00 | CA1 (1.00) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL2130101 | 0.98 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL29790432 | 0.98 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL15347432 | 0.98 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL17891327 | 0.98 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL15548197 | 0.98 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL846287 | 0.98 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL1043957 | 0.98 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL414716 | 0.98 | CA1 (0.95) | CA1CA2CES2CES1NPC1 | |
| P-Anisic Acid SCHEMBL38654440 | 0.98 | CA1 (0.95) | CA1CA2CES2CES1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288161-A1 | METHODS FOR TREATMENT OF THIOL-CONTAINING COMPOUND DEFICIENT CONDITIONS | NATIONAL JEWISH MEDICAL AND RESEARCH CENTER | 2011-11-24 | — | — | US | disclosed |
| US-20110104305-A1 | COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT | DAY BRIAN J | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288161-A1 | METHODS FOR TREATMENT OF THIOL-CONTAINING COMPOUND DEFICIENT CONDITIONS | ABCC1, SLC47A2, SLC47A1 | CA1 2463/4885CA2 1239/4885CES2 351/4885 |
| US-20110104305-A1 | COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT | ABCC1, ABCC2, ABCB1 | CA1 4169/4885CA2 2433/4885CES2 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.