SCHEMBL11570934

SCHEMBL11570934

COC(=O)CCCN1CC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.58
SMN1; SMN2 Q16637 3/20 0.51
PAOX Q6QHF9 1/20 0.50
GLA P06280 1/20 0.49
CYP1A2 P05177 1/20 0.45
MAPK1 P28482 1/20 0.45
FPR3 P25089 1/20 0.44
FPR2 P25090 1/20 0.44
KAT2B Q92831 1/20 0.42
LMNA P02545 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CYP2D6 P10635 1/20 0.41
ADRA2C P18825 1/20 0.41
OPRK1 P41145 1/20 0.41
KCNH2 Q12809 1/20 0.41
EBP Q15125 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31442406 0.92 TSHR (0.50) TSHRSMN1; SMN2PAOXGLACYP1A2
SCHEMBL12323784 0.92 TSHR (0.50) TSHRSMN1; SMN2PAOXGLACYP1A2
SCHEMBL21068872 0.92 TSHR (0.50) TSHRSMN1; SMN2PAOXGLACYP1A2
SCHEMBL15150928 0.92 TSHR (0.54) TSHRSMN1; SMN2PAOXGLACYP1A2
SCHEMBL1856574 0.92 SMN1; SMN2 (0.57) TSHRSMN1; SMN2PAOXGLACYP1A2
SCHEMBL13943130 0.91 PAOX (0.56) TSHRSMN1; SMN2PAOXGLAFPR3
SCHEMBL2127041 0.90 SMN1; SMN2 (0.60) TSHRSMN1; SMN2GLACYP1A2MAPK1
SCHEMBL11732584 0.90 SMN1; SMN2 (0.60) TSHRSMN1; SMN2GLACYP1A2MAPK1
SCHEMBL21068880 0.89 TSHR (0.47) TSHRSMN1; SMN2PAOXGLACYP1A2
Hydrochloric Acid SCHEMBL4924873 0.88 SMN1; SMN2 (0.58) TSHRSMN1; SMN2GLACYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4173580-A Production of β-haloalkylaminosulfonyl halides BASF AKTIENGESELLSCHAFT (DE) 1979-11-06 US disclosed