Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571371 | 0.87 | HTT (0.54) | MAPTUSP2LMNAHTTATM | |
| SCHEMBL11572773 | 0.83 | HTT (0.51) | MAPTUSP2LMNAHTTATM | |
| SCHEMBL7784009 | 0.80 | LMNA (0.51) | MAPTUSP2LMNAATMGAA | |
| 4-Chloroaniline SCHEMBL11573070 | 0.79 | MAPT (0.57) | MAPTUSP2LMNAHTTGAA | |
| SCHEMBL11575800 | 0.79 | POLB (0.49) | MAPTUSP2LMNAHTTATM | |
| 3-Chloroaniline SCHEMBL11574786 | 0.78 | POLB (0.51) | MAPTUSP2LMNAHTTATM | |
| SCHEMBL11574482 | 0.78 | LMNA (0.55) | MAPTUSP2LMNAHTTGAA | |
| SCHEMBL11571174 | 0.78 | MAPT (0.52) | MAPTUSP2LMNAHTTATM | |
| SCHEMBL452517 | 0.78 | — | — | |
| SCHEMBL11570071 | 0.77 | POLB (0.49) | MAPTUSP2LMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | claimed |