Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533272 | 0.84 | TBXA2R (0.46) | AKR1B1HPGDHSD17B10ALDH1A1KDM4E | |
| Methyl Alcohol SCHEMBL11526388 | 0.82 | TBXA2R (0.45) | AKR1B1HPGDHSD17B10ALDH1A1KDM4E | |
| Methane SCHEMBL11528997 | 0.82 | TBXA2R (0.45) | AKR1B1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11666032 | 0.82 | AKR1B1 (0.42) | AKR1B1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11576395 | 0.77 | AKR1B1 (0.46) | AKR1B1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11575568 | 0.76 | SRD5A2 (0.46) | AKR1B1SRD5A2TBXA2RRXRARXRB | |
| SCHEMBL1347195 | 0.74 | AKR1B1 (0.58) | AKR1B1HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11460672 | 0.72 | BRD4 (0.39) | HPGDHSD17B10ALDH1A1KDM4ETSHR | |
| SCHEMBL1346675 | 0.72 | AKR1B1 (0.52) | AKR1B1HPGDHSD17B10KDM4ETSHR | |
| SCHEMBL20861953 | 0.71 | AKR1B1 (0.43) | AKR1B1HPGDHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076838-A | ANTIARTHRITIC, ANALGESICS, ANTIPHLOGISTICS | SANDOZ LTD. (CH) | 1978-02-28 | — | — | US | disclosed |