Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533272 | 0.98 | TBXA2R (0.46) | TBXA2RHPGDHSD17B10KDM4ETSHR | |
| Methyl Alcohol SCHEMBL11526388 | 0.97 | TBXA2R (0.45) | TBXA2RHPGDHSD17B10KDM4ETSHR | |
| SCHEMBL11575568 | 0.87 | SRD5A2 (0.46) | TBXA2RAKR1B1SRD5A2 | |
| Methane SCHEMBL11531376 | 0.84 | ALDH1A1 (0.46) | TBXA2RHPGDTSHRGAAMAPT | |
| SCHEMBL7274546 | 0.83 | TBXA2R (0.46) | TBXA2RHPGDHSD17B10KDM4ETSHR | |
| SCHEMBL11575331 | 0.82 | AKR1B1 (0.41) | TBXA2RHPGDHSD17B10KDM4ETSHR | |
| SCHEMBL11530910 | 0.82 | KDM4E (0.46) | TBXA2RHPGDHSD17B10KDM4ETSHR | |
| SCHEMBL11527244 | 0.82 | ALDH1A1 (0.47) | TBXA2RHPGDTSHRGAAMAPT | |
| SCHEMBL11528818 | 0.81 | TBXA2R (0.42) | TBXA2RMAPTNFKB1LMNA | |
| Methane SCHEMBL10892966 | 0.80 | KDM4E (0.41) | TBXA2RHPGDHSD17B10KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | claimed |
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |