Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501732 | 0.92 | KDM4E (0.78) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL14085807 | 0.88 | KDM4E (0.76) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6415809 | 0.86 | KMT2A (0.84) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7312805 | 0.86 | LMNA (0.71) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6695018 | 0.85 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7632830 | 0.85 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6406681 | 0.85 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6410314 | 0.85 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6699060 | 0.85 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL11302755 | 0.83 | CYP3A4 (0.60) | KDM4EHSD17B10ALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |