Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.55 |
| ▸ | RECQL | P46063 | 5/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 3/20 | 0.55 |
| ▸ | LCK | P06239 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | FYN | P06241 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679483 | 1.00 | KDM6B (0.57) | KDM6BKDM4EHSD17B10TDP1RECQL | |
| SCHEMBL31189097 | 1.00 | KDM6B (0.57) | KDM6BKDM4EHSD17B10TDP1RECQL | |
| SCHEMBL11575407 | 1.00 | KDM6B (0.57) | KDM6BKDM4EHSD17B10TDP1RECQL | |
| SCHEMBL22957012 | 0.84 | KDM6B (0.57) | KDM6BKDM4EHSD17B10TDP1RECQL | |
| SCHEMBL21090091 | 0.84 | KDM6B (0.57) | KDM6BKDM4EHSD17B10TDP1RECQL | |
| SCHEMBL30915529 | 0.84 | KDM6B (0.60) | KDM6BKDM4EHSD17B10TDP1RECQL | |
| SCHEMBL29577557 | 0.84 | KDM6B (0.60) | KDM6BKDM4EHSD17B10TDP1RECQL | |
| SCHEMBL2321567 | 0.84 | KDM6B (0.60) | KDM6BKDM4EHSD17B10TDP1RECQL | |
| SCHEMBL3736877 | 0.84 | KDM6B (0.60) | KDM6BKDM4EHSD17B10TDP1RECQL | |
| SCHEMBL30724831 | 0.83 | KDM6B (0.64) | KDM6BKDM4EHSD17B10TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000034-A1 | Fluorinated amines, compositions and process for preparing said compounds | MERCK & CO. INC. (US) | 1978-12-20 | — | — | EP | disclosed |