SCHEMBL3736877

SCHEMBL3736877

O=C(O)C(Cc1ccc(O)c(O)c1)NF

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.60
KDM4E B2RXH2 6/20 0.58
HSD17B10 Q99714 6/20 0.58
TDP1 Q9NUW8 5/20 0.58
ALOX15 P16050 4/20 0.58
HIF1A Q16665 4/20 0.58
RECQL P46063 4/20 0.58
USP2 O75604 2/20 0.58
ADORA3 P0DMS8 2/20 0.58
HTR2A P28223 2/20 0.58
PTGS2 P35354 2/20 0.58
LCK P06239 2/20 0.58
EGFR P00533 1/20 0.58
FYN P06241 1/20 0.58
PTGS1 P23219 1/20 0.58
SLC7A5 Q01650 1/20 0.58
CA1 P00915 4/20 0.54
CA2 P00918 4/20 0.54
MME P08473 1/20 0.52
ACE P12821 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29577557 1.00 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL30915529 1.00 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL2321567 1.00 KDM6B (0.60) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL22572803 0.87 ALB (0.54) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL30724831 0.86 KDM6B (0.64) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL5063603 0.85 KDM6B (0.62) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL29669984 0.85 KDM6B (0.62) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL29429645 0.85 KDM6B (0.62) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL11575402 0.84 KDM6B (0.57) KDM6BKDM4EHSD17B10TDP1ALOX15
SCHEMBL11575407 0.84 KDM6B (0.57) KDM6BKDM4EHSD17B10TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250049409-A1 METHODS OF QUANTIFYING SKELETAL MUSCLE PERFUSION USING PET IMAGING RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL 2025-02-13 US claimed
CN-119907695-A Novel small gastrin-derived cholecystokinin 2 receptor binding molecules for imaging and targeted radiotherapy 慕尼黑工业大学 2025-04-29 CN disclosed
US-20250049409-A1 METHODS OF QUANTIFYING SKELETAL MUSCLE PERFUSION USING PET IMAGING RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL 2025-02-13 US disclosed
US-20240059724-A1 DEVICE AND CASSETTE FOR PERFORMING A PLURALITY OF SYNTHESIS PROCESSES OF PREPARING A RADIOPHARMACEUTICAL IN SERIES OUT AND OUT CHEMISTRY S.P.R.L. (BE) 2024-02-22 US disclosed
US-11820790-B2 Device and cassette for performing a plurality of synthesis processes of preparing a radiopharmaceutical in series OUT AND OUT CHEMISTRY S.P.R.L. (BE) 2023-11-21 US disclosed
EP-4171592-A1 METHODS FOR DERIVING DOPAMINERGIC NEURONS FROM PLURIPOTENT STEM CELLS Minerva Biotechnologies Corporation (US) 2023-05-03 EP disclosed
WO-2021263241-A1 METHODS FOR DERIVING DOPAMINERGIC NEURONS FROM PLURIPOTENT STEM CELLS MINERVA BIOTECHNOLOGIES CORPORATION (US) 2021-12-30 WO disclosed
EP-3917944-A1 THERAPEUTIC PEPTIDES Cohbar Inc. (US) 2021-12-08 EP disclosed
US-20210322463-A1 METHOD FOR ACCELERATED TISSUE PENETRATION OF COMPOUNDS INTO BRAIN LIKEMINDS INC (US) 2021-10-21 US disclosed
EP-3823679-A1 METHOD FOR ACCELERATED TISSUE PENETRATION OF COMPOUNDS INTO BRAIN Likeminds, Inc. (US) 2021-05-26 EP disclosed
WO-2016184980-A1 METHOD OF PERFORMING A PLURALITY OF SYNTHESIS PROCESSES OF PREPARING A RADIOPHARMACEUTICAL IN SERIES, A DEVICE AND CASSETTE FOR PERFORMING THIS METHOD OUT AND OUT CHEMISTRY S.P.R.L. (BE) 2016-11-24 WO disclosed
EP-2785445-A1 PRODUCTION OF 18F- LABELLED COMPOUNDS COMPRISING HYDROLYTIC DEPROTECTION STEP AND SOLID PHASE EXTRACTION GE Healthcare UK Limited (GB) 2014-10-08 EP disclosed
US-8722014-B2 1 H-[1, 2, 3] triazole substituted amino acids and uses thereof WASHINGTON UNIVERSITY (US) 2014-05-13 US disclosed
WO-2013079578-A1 PRODUCTION OF 18F- LABELLED COMPOUNDS COMPRISING HYDROLYTIC DEPROTECTION STEP AND SOLID PHASE EXTRACTION GE HEALTHCARE LIMITED (GB) 2013-06-06 WO disclosed
US-20100278732-A1 1H-[1, 2, 3] TRIAZOLE SUBSTITUTED AMINO ACIDS AND USES THEREOF WASHINGTON UNIVERSITY (US) 2010-11-04 US disclosed
EP-2101768-A2 USE OF NEUROPROTECTIVE COMPOUNDS FOR OBTAINING DRUGS FOR TREATING NEURODEGENERATIVE DISEASES Les Laboratoires Servier (FR) 2009-09-23 EP disclosed
WO-2008099083-A2 USE OF NEUROPROTECTIVE COMPOUNDS FOR OBTAINING DRUGS FOR TREATING NEURODEGENERATIVE DISEASES LES LABORATOIRES SERVIER (FR) 2008-08-21 WO disclosed
EP-1797029-A1 METHOD OF DEPROTECTION GE Healthcare Limited (GB) 2007-06-20 EP disclosed
CN-1894173-A Preparation of 18-fluoro-labeled aromatic amino acids UNIV EBERHARD KARLS (DE) 2007-01-10 CN disclosed
WO-2006037950-A1 METHOD OF DEPROTECTION GE HEALTHCARE LIMITED (GB) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100278732-A1 1H-[1, 2, 3] TRIAZOLE SUBSTITUTED AMINO ACIDS AND USES THEREOF SLC7A1, SLC1A5, SLC1A3 KDM6B 4699/4885KDM4E 4738/4885HSD17B10 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.