SCHEMBL11575413

SCHEMBL11575413

CCc1cc(C(=O)c2ccc(OC)c(CC)c2)ccc1OC

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.66
CYP2C19 P33261 2/20 0.66
TSHR P16473 2/20 0.66
CYP3A4 P08684 1/20 0.66
CYP2C9 P11712 1/20 0.66
ALDH1A1 P00352 5/20 0.59
LMNA P02545 1/20 0.59
HTT P42858 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
SLC22A6 Q4U2R8 1/20 0.56
SLC22A8 Q8TCC7 1/20 0.56
GAA P10253 1/20 0.56
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
ACHE P22303 3/20 0.53
TUBB4A P04350 2/20 0.51
TUBB P07437 2/20 0.51
TUBA3C P0DPH7 2/20 0.51
TUBA1B P68363 2/20 0.51
TUBA4A P68366 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9449884 0.87 CYP1A2 (0.51) CYP1A2CYP2C19TSHRCYP3A4CYP2C9
SCHEMBL6342125 0.87 ALDH1A1 (0.71) ALDH1A1HTTL3MBTL1GAAMEN1
SCHEMBL7368821 0.87 CA12 (0.67) TSHRALDH1A1LMNAHTTMEN1
SCHEMBL4820827 0.86 TSHR (0.73) CYP1A2CYP2C19TSHRCYP3A4CYP2C9
SCHEMBL18360020 0.85 MAPK1 (0.66) CYP1A2CYP2C19TSHRCYP3A4CYP2C9
SCHEMBL17067577 0.85 MAPT (0.60) CYP1A2CYP2C19TSHRCYP3A4CYP2C9
SCHEMBL16955936 0.85 ALDH1A1 (0.54) CYP1A2CYP2C19TSHRCYP3A4CYP2C9
SCHEMBL18755183 0.82 PDE4D (0.54) TSHRALDH1A1MEN1KMT2AHPGD
SCHEMBL17758615 0.82 SLC6A2 (0.56) CYP1A2CYP2C19CYP3A4CYP2C9ALDH1A1
SCHEMBL17758616 0.82 ALDH1A1 (0.56) CYP1A2CYP2C19TSHRCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4115413-A ACID FREE BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed