Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828395 | 1.00 | TSHR (0.62) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL17713234 | 1.00 | TSHR (0.62) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL829178 | 1.00 | TSHR (0.62) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6927779 | 0.98 | TSHR (0.61) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL30871905 | 0.95 | TSHR (0.64) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL828233 | 0.93 | TSHR (0.65) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL4820297 | 0.93 | TSHR (0.65) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL829547 | 0.93 | TSHR (0.65) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL828828 | 0.93 | TSHR (0.65) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL828955 | 0.93 | TSHR (0.65) | TSHRTDP1L3MBTL1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097456-A | Preparation of acetylene-substituted polyimide oligomers and polyimide polymers | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1978-06-27 | — | — | US | disclosed |