Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SPOP | O43791 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11104711 | 1.00 | PLCG1 (0.67) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11101003 | 0.93 | PLCG1 (0.60) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11100411 | 0.92 | PLCG1 (0.59) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11654441 | 0.91 | PLCG1 (0.81) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11097617 | 0.91 | PLCG1 (0.81) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL8766584 | 0.90 | PLCG1 (0.83) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL28528206 | 0.90 | PLCG1 (0.83) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL8766580 | 0.90 | PLCG1 (0.83) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11305923 | 0.88 | PLCG1 (0.66) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11101773 | 0.88 | PLCG1 (0.66) | PLCG1MAPTL3MBTL1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115643-A | Process for 3-chloro cephalosporins | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | disclosed |