Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SPOP | O43791 | 1/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11104711 | 0.93 | PLCG1 (0.67) | PLCG1L3MBTL1SPOPNAPEPLDMAPT | |
| SCHEMBL11575527 | 0.93 | PLCG1 (0.67) | PLCG1L3MBTL1SPOPNAPEPLDMAPT | |
| SCHEMBL11100411 | 0.88 | PLCG1 (0.59) | PLCG1L3MBTL1HTTSPOPMAPT | |
| SCHEMBL11101773 | 0.85 | PLCG1 (0.66) | PLCG1L3MBTL1HTTNAPEPLDMAPT | |
| SCHEMBL11305923 | 0.85 | PLCG1 (0.66) | PLCG1L3MBTL1HTTNAPEPLDMAPT | |
| SCHEMBL28528206 | 0.84 | PLCG1 (0.83) | PLCG1L3MBTL1HTTNAPEPLDMAPT | |
| SCHEMBL8766580 | 0.84 | PLCG1 (0.83) | PLCG1L3MBTL1HTTNAPEPLDMAPT | |
| SCHEMBL8766584 | 0.84 | PLCG1 (0.83) | PLCG1L3MBTL1HTTNAPEPLDMAPT | |
| SCHEMBL11098923 | 0.84 | PLCG1 (0.61) | PLCG1L3MBTL1NAPEPLDMAPTMEN1 | |
| SCHEMBL11654441 | 0.83 | PLCG1 (0.81) | PLCG1L3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014567-B1 | PROCESSES FOR PREPARATION OF BETA-LACTAM COMPOUNDS | ELI LILLY AND COMPANY (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4271305-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4226986-A | 7-ACYLAMINO-3-HYDROXY-3-CEPHEM COMPOUND, TRIARYL PHOSPHITE DIHALIDE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0014567-A1 | Processes for preparation of beta-lactam compounds | ELI LILLY AND COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |