Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15109754 | 0.88 | HTR2A (0.41) | HTR2AHTR2CHTR2BKDM1ASLC6A2 | |
| Maleic Acid SCHEMBL11577738 | 0.85 | DRD2 (0.39) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL192318 | 0.79 | SRD5A1 (0.47) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL29443582 | 0.79 | SRD5A1 (0.47) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL1859026 | 0.79 | SRD5A1 (0.47) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL29443577 | 0.79 | SRD5A1 (0.47) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| SCHEMBL1857673 | 0.79 | SRD5A1 (0.47) | HTR2AHTR2CHTR2BKDM1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL26664227 | 0.78 | SRD5A1 (0.46) | HTR2AHTR2CHTR2BKDM1AACHE | |
| Hydrochloric Acid SCHEMBL17579539 | 0.78 | SRD5A1 (0.46) | HTR2AHTR2CHTR2BKDM1AACHE | |
| SCHEMBL7895243 | 0.77 | HTR2C (0.47) | HTR2AHTR2CHTR2BKDM1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096173-A | Chlorinated 1-aminoindane N-methyl transferase inhibitors | ELI LILLY AND COMPANY (US) | 1978-06-20 | — | — | US | claimed |
| US-4096173-A | Chlorinated 1-aminoindane N-methyl transferase inhibitors | ELI LILLY AND COMPANY (US) | 1978-06-20 | — | — | US | disclosed |