Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25626596 | 0.80 | CHRNB4 (0.38) | MAPTKDM4EGAACHRNB4CHRNA3 | |
| SCHEMBL12862906 | 0.78 | MAPT (0.39) | MAPTKDM4EGAACHRNB4CHRNA3 | |
| SCHEMBL15013787 | 0.77 | MAPT (0.38) | MAPTKDM4EGAACHRNB4CHRNA3 | |
| SCHEMBL5285093 | 0.77 | MAPT (0.39) | MAPTKDM4EGAACHRNB4CHRNA3 | |
| SCHEMBL17644228 | 0.76 | CA2 (0.40) | CA2 | |
| SCHEMBL13862088 | 0.76 | CA2 (0.39) | MAPTKDM4EGAACHRNB4CHRNA3 | |
| SCHEMBL15013577 | 0.74 | GRM2 (0.38) | MAPTKDM4EGAACHRNB4CHRNA3 | |
| SCHEMBL3632741 | 0.73 | CA2 (0.45) | MAPTSMN1; SMN2CA2LMNAHTT | |
| SCHEMBL15011154 | 0.73 | GRM2 (0.43) | MAPTKDM4EGAACHRNB4CHRNA3 | |
| SCHEMBL1168316 | 0.73 | PRKCI (0.41) | MAPTKDM4EGAACHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155915-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | disclosed |