Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813210 | 0.90 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL6813517 | 0.88 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL2581955 | 0.87 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL29877685 | 0.85 | MAOB (0.58) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL11318579 | 0.84 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL6809682 | 0.83 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL11693468 | 0.83 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL6813395 | 0.82 | HDAC8 (0.64) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL16431269 | 0.81 | GRM5 (0.65) | NPC1RAB9ASMN1; SMN2KDM4ETP53 | |
| SCHEMBL6787762 | 0.81 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080321-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |