SCHEMBL11575824

SCHEMBL11575824

CCCCCc1cc(C)ccc1C(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.44
LMNA P02545 1/20 0.44
CHRM1 P11229 1/20 0.44
SLC6A2 P23975 1/20 0.44
ADRA1A P35348 1/20 0.44
HTR2B P41595 1/20 0.44
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TYR P14679 2/20 0.39
MAPT P10636 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX5 P09917 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GCGR P47871 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL29240397 0.84 TRPA1 (0.50) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL11443443 0.82 TRPA1 (0.48) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL29773153 0.81 TRPA1 (0.41) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL17318269 0.81 TYR (0.41) LMNACHRM1SLC6A2CNR1CNR2
SCHEMBL31190193 0.80 TYR (0.42) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL31190191 0.79 TRPA1 (0.52) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL599002 0.79 TRPA1 (0.52) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL11443446 0.78 TRPA1 (0.52) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL3842087 0.78 TAAR1 (0.60) TRPA1LMNACHRM1SLC6A2ADRA1A
SCHEMBL6562301 0.77 TAAR1 (0.59) CNR1CNR2MEN1KMT2ATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850345-A Quinoline functional nitrogen heterocyclic carbene ruthenium complex with multiple anti-cancer activities and preparation method thereof 浙江树人学院 2023-03-28 CN disclosed
US-4113645-A QUATERNARY AMMONIUM SALT DISPERSANT POLAK'S FRUTAL WORKS, INC. (US) 1978-09-12 US disclosed