Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 8/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11364438 | 0.97 | CFTR (0.49) | CFTRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11576610 | 0.97 | CFTR (0.49) | CFTRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9550350 | 0.92 | CFTR (0.55) | CFTRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9629692 | 0.85 | CFTR (0.49) | CFTRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29401067 | 0.85 | HSD17B10 (0.50) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL9492931 | 0.85 | HSD17B10 (0.50) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL29441324 | 0.85 | HSD17B10 (0.50) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL1770132 | 0.85 | HSD17B10 (0.50) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL109108 | 0.85 | HSD17B10 (0.50) | KDM4EALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL14331409 | 0.84 | CA12 (0.44) | KDM4EALDH1A1HPGDHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097456-A | Preparation of acetylene-substituted polyimide oligomers and polyimide polymers | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1978-06-27 | — | — | US | disclosed |