Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550350 | 0.92 | CFTR (0.55) | CFTRKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL8928305 | 0.87 | CA1 (0.53) | ALDH1A1MAPTATMNOTUMCA1 | |
| SCHEMBL11576610 | 0.85 | CFTR (0.49) | CFTRKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11364438 | 0.85 | CFTR (0.49) | CFTRKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11575847 | 0.85 | CFTR (0.51) | CFTRKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL24682887 | 0.81 | NPC1 (0.51) | KDM4EALDH1A1MAPTATMNOTUM | |
| SCHEMBL12117414 | 0.81 | SMN1; SMN2 (0.47) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL22263091 | 0.79 | CFTR (0.73) | CFTRKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL12310503 | 0.75 | CFTR (0.45) | CFTRKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL126043 | 0.75 | KDM4E (0.69) | KDM4EALDH1A1MAPTHSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120826-A | Polyamide-imide polymers having fluorine-containing linking groups | HOECHST CELANESE CORP. (US) | 1992-06-09 | — | — | US | disclosed |
| US-5120825-A | Heat resistant hybrid | HOECHST CELANESE CORP. (US) | 1992-06-09 | — | — | US | disclosed |
| US-5109107-A | Excellent flow properties and hydrolytic stability | HOECHT CELANESE CORP. (US) | 1992-04-28 | — | — | US | disclosed |