Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.86 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.86 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.70 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 1/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.70 |
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | DRD4 | P21917 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | HRH1 | P35367 | 1/20 | 0.70 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.70 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5870675 | 0.93 | OPRM1 (0.74) | OPRM1SIGMAR1CHRM3SLC22A1NR1I2 | |
| SCHEMBL6045571 | 0.92 | OPRM1 (1.00) | OPRM1SIGMAR1CHRM3SLC22A1NR1I2 | |
| Hydrochloric Acid SCHEMBL29651340 | 0.91 | OPRM1 (0.97) | OPRM1SIGMAR1CHRM3SLC22A1NR1I2 | |
| Oxalic Acid SCHEMBL6045624 | 0.90 | OPRM1 (0.95) | OPRM1SIGMAR1CHRM3SLC22A1NR1I2 | |
| SCHEMBL11577737 | 0.88 | OPRM1 (0.86) | OPRM1SIGMAR1CHRM3SLC22A1NR1I2 | |
| SCHEMBL925917 | 0.85 | OPRM1 (0.86) | OPRM1SIGMAR1CHRM3SLC22A1NR1I2 | |
| SCHEMBL15920014 | 0.85 | OPRM1 (0.86) | OPRM1SIGMAR1CHRM3SLC22A1NR1I2 | |
| SCHEMBL15920012 | 0.85 | OPRM1 (0.86) | OPRM1SIGMAR1CHRM3SLC22A1NR1I2 | |
| SCHEMBL24726582 | 0.84 | OPRM1 (0.80) | OPRM1SIGMAR1OPRD1OPRK1 | |
| SCHEMBL30110433 | 0.84 | OPRM1 (0.80) | OPRM1SIGMAR1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29828-E | ANALGESICS, ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1978-11-07 | — | — | US | claimed |
| US-RE29828-E | ANALGESICS, ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1978-11-07 | — | — | US | disclosed |