SCHEMBL11577016

SCHEMBL11577016

CC(C)(C)c1c(O)ccc(C/C=C/c2ccccc2)c1C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MAPT P10636 2/20 0.50
RECQL P46063 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX15 P16050 1/20 0.50
PTGER4 P35408 2/20 0.43
PTGER3 P43115 2/20 0.43
PTGER2 P43116 2/20 0.43
PAM P19021 1/20 0.39
TNFRSF1A P19438 1/20 0.38
HTR2A P28223 3/20 0.37
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.36
PKM P14618 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11577019 1.00 MEN1 (0.50) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11576278 0.83 KDM4E (0.46) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11576276 0.83 KDM4E (0.46) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11575693 0.81 TNFRSF1A (0.48) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11575696 0.81 TNFRSF1A (0.48) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11576908 0.80 ALDH1A1 (0.52) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11578530 0.80 MAPT (0.43) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11578533 0.80 MAPT (0.43) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11577189 0.80 ALDH1A1 (0.52) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL11576912 0.80 ALDH1A1 (0.52) MEN1KMT2AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4082814-A DI-TERT-BUTYL-CINNAMYL PHENOLS, DI-TERT-BUTYL-DIHYDROCINNAMYL PHENONLS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1978-04-04 US disclosed
US-3973040-A Certain cinnamyl phenols as growth inhibitors for mosquito larvae THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-08-03 US disclosed