Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785981 | 0.86 | MEN1 (0.47) | MAPTPOLBMAPK1TDP1GAA | |
| SCHEMBL8347090 | 0.85 | PLA2G4B (0.51) | MAPTAKR1C3AKR1C2AKR1C1NPSR1 | |
| SCHEMBL1784674 | 0.84 | LMNA (0.53) | MAPTTSHRMAPK1TDP1AKR1C3 | |
| SCHEMBL28720949 | 0.83 | TSHR (0.68) | MAPTTSHRPOLBHSD17B10GAA | |
| SCHEMBL28721663 | 0.83 | TSHR (0.48) | MAPTTSHRPOLBHSD17B10GAA | |
| SCHEMBL11611705 | 0.83 | MAPT (0.44) | MAPTTSHRPOLBMAPK1TDP1 | |
| SCHEMBL7375557 | 0.83 | TSHR (0.48) | MAPTTSHRPOLBMAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL11778515 | 0.82 | LMNA (0.52) | MAPTTSHRMAPK1TDP1AKR1C3 | |
| SCHEMBL1645081 | 0.82 | TSHR (0.53) | MAPTTSHRPOLBMAPK1HSD17B10 | |
| SCHEMBL8887345 | 0.82 | LMNA (0.49) | MAPTPOLBMAPK1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607357-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | Astrazeneca AB (SE) | 2013-06-26 | — | — | EP | disclosed |
| US-4066456-A | COLOR PHOTOGRAPHIC FILMS | GAF CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |