Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576481 | 0.80 | CTSA (0.31) | — | |
| SCHEMBL11576654 | 0.79 | PPARD (0.47) | TSHRPPARDMAPTMAPK1GAA | |
| SCHEMBL6750640 | 0.78 | TSHR (0.50) | TSHRPPARDMAPTMAPK1GAA | |
| SCHEMBL8463197 | 0.74 | GAA (0.45) | TSHRPPARDMAPTMAPK1GAA | |
| SCHEMBL15317935 | 0.72 | TSHR (0.48) | TSHRPPARDMAPTMAPK1GAA | |
| SCHEMBL15032899 | 0.72 | TSHR (0.52) | TSHRPPARDMAPTMAPK1GAA | |
| SCHEMBL5429281 | 0.69 | TSHR (0.37) | TSHRPPARDGAAPOLBTP53 | |
| SCHEMBL9633264 | 0.69 | TSHR (0.55) | TSHRPPARDMAPTMAPK1GAA | |
| SCHEMBL11576647 | 0.69 | PPARD (0.44) | TSHRPPARDMAPTMAPK1GAA | |
| SCHEMBL6748637 | 0.67 | HSD17B10 (0.41) | TSHRPPARDMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4102830-A | Diol-phosphonates as flame-retardants in polyurethane foam | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1978-07-25 | — | — | US | disclosed |