Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838280 | 0.80 | CA12 (0.30) | — | |
| SCHEMBL11576647 | 0.79 | PPARD (0.44) | GAAKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL8497949 | 0.78 | CTSA (0.33) | GAAATM | |
| SCHEMBL35874 | 0.76 | TSHR (0.44) | GAAKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL5050661 | 0.74 | MEN1 (0.63) | GAAKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL19979585 | 0.74 | MEN1 (0.63) | GAAKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL11577243 | 0.74 | TSHR (0.39) | GAATSHRPPARDTDP1MAPT | |
| SCHEMBL6750640 | 0.73 | TSHR (0.50) | GAATSHRPPARDTDP1MAPT | |
| SCHEMBL11365714 | 0.73 | FDPS (0.34) | TDP1 | |
| SCHEMBL530398 | 0.72 | CYP2C9 (0.56) | GAAKMT2AMEN1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981612-A | Production of flameproofed, rigid, isocyanate-based foams | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| EP-0719807-B1 | Process for the preparation of flame-proofed rigid foams based on isocyanate | BASF SCHWARZHEIDE GMBH (DE) | 1999-11-03 | — | — | EP | disclosed |
| EP-0719807-A2 | Process for the preparation of flame-proofed rigid foams based on isocyanate | BASF SCHWARZHEIDE GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |