Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577377 | 0.91 | MAPT (0.49) | MAPTALDH1A1L3MBTL1BCL9CTNNB1 | |
| SCHEMBL9091623 | 0.85 | MAPT (0.57) | MAPTALDH1A1L3MBTL1BCL9CTNNB1 | |
| SCHEMBL11063250 | 0.84 | MAPT (0.53) | MAPTALDH1A1L3MBTL1BCL9CTNNB1 | |
| SCHEMBL11060688 | 0.84 | MAPT (0.53) | MAPTALDH1A1L3MBTL1BCL9CTNNB1 | |
| SCHEMBL11064795 | 0.84 | MAPT (0.53) | MAPTALDH1A1L3MBTL1BCL9CTNNB1 | |
| SCHEMBL11578616 | 0.82 | ASAH1 (0.48) | ALDH1A1LMNAKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL31404165 | 0.82 | BCL9 (0.58) | MAPTALDH1A1L3MBTL1BCL9CTNNB1 | |
| SCHEMBL29836400 | 0.82 | BCL9 (0.58) | MAPTALDH1A1L3MBTL1BCL9CTNNB1 | |
| SCHEMBL30071720 | 0.82 | BCL9 (0.58) | MAPTALDH1A1L3MBTL1BCL9CTNNB1 | |
| SCHEMBL10358150 | 0.81 | MAPT (0.45) | MAPTALDH1A1L3MBTL1BCL9CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097665-A | Diacylnucleosides and process for preparing the same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-06-27 | — | — | US | disclosed |