Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060688 | 1.00 | MAPT (0.53) | MAPTL3MBTL1CRHBPCRHR2MGLL | |
| SCHEMBL11063250 | 1.00 | MAPT (0.53) | MAPTL3MBTL1CRHBPCRHR2MGLL | |
| SCHEMBL11065666 | 0.93 | MAPT (0.47) | MAPTL3MBTL1CRHBPCRHR2MGLL | |
| SCHEMBL9091623 | 0.91 | MAPT (0.57) | MAPTL3MBTL1CRHBPCRHR2MGLL | |
| SCHEMBL11577377 | 0.90 | MAPT (0.49) | MAPTL3MBTL1CRHBPCRHR2MGLL | |
| SCHEMBL10358150 | 0.86 | MAPT (0.45) | MAPTL3MBTL1CRHBPCRHR2MGLL | |
| SCHEMBL1768015 | 0.85 | MAPT (0.54) | MAPTL3MBTL1CRHBPCRHR2MGLL | |
| SCHEMBL11577384 | 0.84 | MAPT (0.54) | MAPTL3MBTL1CRHBPCRHR2MGLL | |
| SCHEMBL2944802 | 0.84 | ALDH1A1 (0.47) | MAPTL3MBTL1CRHBPCRHR2MGLL | |
| SCHEMBL2952788 | 0.84 | ALDH1A1 (0.47) | MAPTL3MBTL1CRHBPCRHR2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112344-A1 | AMPHIPATHIC COMPOUNDS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-07-04 | — | — | EP | disclosed |
| WO-1983004412-A1 | AMPHIPATHIC COMPOUNDS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-12-22 | — | — | WO | disclosed |