SCHEMBL1157764

SCHEMBL1157764

CC(C)Oc1ccc(SSc2ccc(OC(C)C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 1/20 0.50
KMT2A Q03164 3/20 0.48
PARP10 Q53GL7 1/20 0.47
POLB P06746 2/20 0.44
GAA P10253 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
GLA P06280 1/20 0.42
ALDH1A1 P00352 3/20 0.41
PTGIR P43119 1/20 0.41
RAB9A P51151 1/20 0.38
BRD4 O60885 1/20 0.37
BRPF1 P55201 1/20 0.37
LMNA P02545 2/20 0.37
TP53 P04637 2/20 0.37
MAPK1 P28482 1/20 0.37
PTPN5 P54829 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23917765 0.85 PTGIR (0.51) ALDH1A3KMT2APARP10POLBGAA
SCHEMBL125543 0.84 ALDH1A3 (0.64) ALDH1A3KMT2APARP10POLBGAA
SCHEMBL7055444 0.83 ALDH1A3 (0.48) ALDH1A3KMT2APARP10POLBGAA
SCHEMBL5852771 0.81 ALDH1A3 (0.47) ALDH1A3KMT2APARP10POLBGAA
SCHEMBL23312314 0.81 ALDH1A3 (0.47) ALDH1A3KMT2APARP10POLBGAA
SCHEMBL10345935 0.79 ALDH1A3 (0.45) ALDH1A3KMT2APARP10POLBGAA
Hydrogen Peroxide SCHEMBL28902806 0.78 KMT2A (0.70) ALDH1A3KMT2APARP10POLBGAA
SCHEMBL23917965 0.78 PTGIR (0.50) ALDH1A3KMT2APARP10GAACYP1A2
SCHEMBL7050105 0.78 SLC6A4 (0.48) ALDH1A3KMT2APARP10POLBGAA
SCHEMBL10504209 0.78 ACACB (0.39) ALDH1A3POLBGAACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7888417-B2 core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core ACUSHNET COMPANY (US) 2011-02-15 US disclosed
US-20080261722-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-10-23 US disclosed
US-20080227567-A1 COMPOSITIONS FOR USE IN GOLF BALLS ACUSHNET COMPANY 2008-09-18 US disclosed
US-20080176678-A1 Compositions for Use in Golf Balls ACUSHNET COMPANY 2008-07-24 US disclosed
EP-1199766-B1 Non-aqueous secondary battery having enhanced discharge capacity retention UBE INDUSTRIES (JP) 2008-05-28 EP disclosed
US-7361711-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-22 US disclosed
US-7358310-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7358309-B2 core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7358308-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-20060281586-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
US-20060281587-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
US-20050245657-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-20050245652-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-6866966-B2 Efficiency UBE INDUSTRIES, LTD. (JP) 2005-03-15 US disclosed
EP-0683774-B1 HYPOLIPIDAEMIC COMPOUNDS WELLCOME FOUND (GB) 2002-10-09 EP disclosed
US-20020122988-A1 Efficiency UBE INDUSTRIES, LTD. (JP) 2002-09-05 US disclosed
EP-1199766-A2 Non-aqueous secondary battery having enhanced discharge capacity retention Ube Industries, Ltd. (JP) 2002-04-24 EP disclosed
US-5723458-A 1,4-BENZOTHIAZEPINES GLAXO WELLCOME INC. (US) 1998-03-03 US disclosed
WO-1994018184-A1 HYPOLIPIDAEMIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1994-08-18 WO disclosed
US-5194539-A Of ethylenically unsaturated monomers where the aqueous dispersion is free from odor causing xanthogen disulfide RHONE-POULENC CHIMIE (FR) 1993-03-16 US disclosed