⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12307012 | 0.80 | MAPT (0.61) | — | |
| SCHEMBL14461124 | 0.80 | MAPT (0.61) | — | |
| SCHEMBL12307010 | 0.79 | — | — | |
| SCHEMBL10000190 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL17871655 | 0.77 | MAPT (0.53) | — | |
| SCHEMBL8291119 | 0.76 | — | — | |
| SCHEMBL3987405 | 0.76 | — | — | |
| 5-Methylfurfural SCHEMBL51606 | 0.76 | — | — | |
| SCHEMBL183148 | 0.76 | — | — | |
| 5-Methylfurfural SCHEMBL4463513 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204407-B1 | PROCESS | GIVAUDAN SA (CH) | 2024-06-19 | — | — | EP | claimed |
| US-20230312506-A1 | PROCESS | GIVAUDAN SA (CH) | 2023-10-05 | — | — | US | claimed |
| EP-4204407-A1 | PROCESS | Givaudan SA (CH) | 2023-07-05 | — | — | EP | claimed |
| CN-103265559-A | Substituted tricyclic benzoquinone compound and preparation method and application thereof | UNIV PLA 2ND MILITARY MEDICAL | 2013-08-28 | — | — | CN | claimed |
| EP-4204407-B1 | PROCESS | GIVAUDAN SA (CH) | 2024-06-19 | — | — | EP | disclosed |
| US-20240139087-A1 | ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS | GIVAUDAN SA (CH) | 2024-05-02 | — | — | US | disclosed |
| US-20240132487-A1 | SUBSTITUTED AZACYLES AS TRMP8 MODULATORS | GIVAUDAN SA (CH) | 2024-04-25 | — | — | US | disclosed |
| EP-4291553-A1 | ORGANIC COMPOUNDS AS TRPM8 ACTIVATORS | Givaudan SA (CH) | 2023-12-20 | — | — | EP | disclosed |
| CN-116867775-A | Organic compounds as TRPM8 activators | 奇华顿股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-20230312506-A1 | PROCESS | GIVAUDAN SA (CH) | 2023-10-05 | — | — | US | disclosed |
| EP-4204407-A1 | PROCESS | Givaudan SA (CH) | 2023-07-05 | — | — | EP | disclosed |
| CN-116209659-A | Method | 奇华顿股份有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-4113942-A | ANTIBACTERIAL | PFIZER INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-4109085-A | ANTIBIOTICS, BACTERICIDES | PFIZER INC. (US) | 1978-08-22 | — | — | US | disclosed |
| US-4109083-A | CEPHALOSPORIN ANTIBIOTICS | PFIZER INC. (US) | 1978-08-22 | — | — | US | disclosed |
| US-4045437-A | ANTIBACTERIAL | PFIZER, INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-4045436-A | ANTIBACTERIAL | PFIZER INC. (US) | 1977-08-30 | — | — | US | disclosed |
| US-4039532-A | BACTERICIDES | PFIZER INC. (US) | 1977-08-02 | — | — | US | disclosed |
| US-4039533-A | CEPHALOSPORINS | PFIZER INC. (US) | 1977-08-02 | — | — | US | disclosed |
| US-3966719-A | ANTIBACTERIAL | PFIZER INC. (US) | 1976-06-29 | — | — | US | disclosed |