Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 6/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577977 | 1.00 | ATM (0.48) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL3695169 | 0.90 | ATM (0.43) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL3695165 | 0.90 | ATM (0.43) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL5356475 | 0.88 | HCAR2 (0.42) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL5370758 | 0.88 | HCAR2 (0.42) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL25198124 | 0.88 | HCAR2 (0.42) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL27884001 | 0.88 | HCAR2 (0.42) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL5356470 | 0.88 | HCAR2 (0.42) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL5370765 | 0.88 | HCAR2 (0.42) | ATMHCAR2TSHRALDH1A1CYP3A4 | |
| SCHEMBL27883977 | 0.88 | HCAR2 (0.42) | ATMHCAR2TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29772-E | IMPACT STRENGTH, CLARITY, WEATHER RESISTANCE | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | disclosed |