Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.62 |
| ▸ | HTR1B | P28222 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LSS | P48449 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529925 | 0.94 | HTR7 (0.64) | HTR7HTR1BALDH1A1KDM4ELSS | |
| SCHEMBL7535239 | 0.88 | HTR7 (0.77) | HTR7HTR1BALDH1A1KDM4ELMNA | |
| SCHEMBL14084399 | 0.85 | HTR7 (0.55) | HTR7HTR1BALDH1A1KDM4EMAPT | |
| SCHEMBL14108022 | 0.84 | HTR7 (0.57) | HTR7HTR1BALDH1A1KDM4ELSS | |
| SCHEMBL4901032 | 0.82 | HTR7 (0.55) | HTR7HTR1BALDH1A1KDM4ELSS | |
| SCHEMBL15721462 | 0.82 | HTR7 (0.51) | HTR7HTR1BALDH1A1KDM4ELSS | |
| SCHEMBL8403606 | 0.81 | HTR7 (0.68) | HTR7HTR1BALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28214028 | 0.81 | HTR1B (0.49) | HTR7HTR1BALDH1A1KDM4ELSS | |
| SCHEMBL16093361 | 0.81 | HTR7 (0.54) | HTR7HTR1BALDH1A1KDM4ELSS | |
| SCHEMBL14084396 | 0.80 | HTR7 (0.56) | HTR7HTR1BALDH1A1KDM4ELSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4090988-A | Polyurethane foam preparation using pyridine ether catalysts | OLIN CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |