Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843364 | 0.86 | ESR1 (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11580833 | 0.86 | CNR1 (0.36) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11578934 | 0.84 | CNR2 (0.43) | TLR2 | |
| SCHEMBL11578946 | 0.84 | CNR2 (0.43) | TLR2 | |
| SCHEMBL11868646 | 0.81 | TLR2 (0.34) | PLA2G4BTLR2 | |
| SCHEMBL11580879 | 0.79 | ESR1 (0.34) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11870675 | 0.79 | CNR2 (0.36) | TLR2 | |
| SCHEMBL11580872 | 0.79 | CNR2 (0.40) | TLR2 | |
| SCHEMBL11579144 | 0.79 | CNR2 (0.40) | TLR2 | |
| SCHEMBL235122 | 0.78 | ESR1 (0.52) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071497-A | LIGHT AND HEAT RESISTANT POLYOLEFINS | CIBA-GEIGY CORPORATION (US) | 1978-01-31 | — | — | US | disclosed |
| US-3954839-A | LIGHT AND HEAT STABILIZERS FOR POLYOLEFINS | CIBA-GEIGY CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |