Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580010 | 0.86 | ESR1 (0.42) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9843396 | 0.81 | ESR1 (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL16281811 | 0.79 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5909518 | 0.79 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL78664 | 0.79 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL13509243 | 0.79 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL539846 | 0.79 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1264788 | 0.79 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL439370 | 0.79 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL30573070 | 0.79 | ESR1 (0.68) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436936-A2 | Lipid selective anti-oxidants, their production and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-17 | — | — | EP | disclosed |